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. 2021 Feb 12;14(2):147. doi: 10.3390/ph14020147

Table 4.

Chromatographic parameters for compounds 1 to 63.

Rf Rf/PSA RM RM/MW RM/VM RM 0 S
1 Diazepam 0.33 0.0101 0.308 0.00108 0.00123 3.578 −4.176
2 Temazepam 0.50 0.0095 0.000 0.00000 0.00000 3.050 −3.798
3 Alprazolam 0.22 0.0058 0.550 0.00178 0.00204 3.254 −3.877
4 Medazepam 0.56 0.0359 −0.105 −0.00039 −0.00042 2.528 −3.035
5 Bromazepam 0.51 0.0094 −0.017 −0.00005 −0.00007 2.496 −3.269
6 Chlordiazepoxide 0.62 0.0117 −0.213 −0.00070 −0.00079 2.131 −2.551
7 Midazolam 0.58 0.0230 −0.140 −0.00043 −0.00051 2.235 −2.741
8 Oxazepam 0.60 0.0097 −0.176 −0.00061 −0.00073 2.864 −3.752
9 Lorazepam 0.61 0.0099 −0.194 −0.00060 −0.00076 3.031 −4.037
10 Lormetazepam 0.49 0.0093 0.017 0.00005 0.00006 3.303 −4.207
11 Clorazepate 0.47 0.0060 0.052 0.00017 0.00020 3.117 −3.840
12 Ibuprofen 0.46 0.0122 0.078 0.00038 0.00037 4.139 −4.895
13 Zolpidem 0.68 0.0181 −0.327 −0.00106 −0.00109 1.744 −2.341
14 Tamoxifen 0.48 0.0381 0.043 0.00012 0.00015 5.041 −5.908
15 Propranolol 0.82 0.0198 −0.659 −0.00254 −0.00254 2.059 −3.004
16 Ranitidine 0.82 0.0074 −0.659 −0.00208 −0.00220 0.343 −0.518
17 Methyldopa 0.98 0.0094 −1.690 −0.00800 −0.00914 2.480 −0.197
18 Amizepin 0.55 0.0119 −0.087 −0.00033 −0.00040 2.484 −3.221
19 Enalapril 0.82 0.0085 −0.659 −0.00175 −0.00175 2.035 −2.994
20 Paracetamol 0.85 0.0172 −0.753 −0.00498 −0.00542 0.459 −1.500
21 Aspirin 0.76 0.0119 −0.501 −0.00278 −0.00328 1.301 −2.204
22 Cefuroxime 0.77 0.0039 −0.525 −0.00124 −0.00160 2.023 −3.307
23 Theophylline 0.79 0.0114 −0.575 −0.00319 −0.00110
24 Verapamil 0.77 0.0120 −0.525 −0.00115 −0.00036
25 Clobazam 0.50 0.0124 0 0 0
26 Mitrazapin 0.71 0.0366 −0.389 −0.00147 −0.00049
27 Promazine 0.71 0.0223 −0.389 −0.00137 −0.00045
28 Phenytoin 0.70 0.0120 −0.368 −0.00146 −0.00051
29 Hydroxyzine 0.76 0.0212 −0.501 −0.00134 −0.00046
30 Mianserin 0.77 0.1185 −0.525 −0.00199 −0.00065
31 Valproic acid 0.54 0.1185 −0.070 −0.00048 −0.00013
32 Zopiclone 0.80 0.1185 −0.602 −0.00155 −0.00059
33 Haloperidol 0.78 0.0192 −0.550 −0.00146 −0.00053
34 Risperidone 0.55 0.0089 −0.087 −0.00021 −0.00008
35 Loperamide 0.53 0.0121 −0.052 −0.00011 −0.00004
36 Phenylbutazone 0.39 0.0096 0.194 0.00063 0.00021
37 Clonidine 0.83 0.0234 −0.689 −0.00299 −0.00110
38 PABA 0.85 0.0134 −0.753 −0.00549 −0.00170
39 Propylparaben 0.61 0.0131 −0.194 −0.00108 −0.00032
40 Methylparaben 0.72 0.0155 −0.410 −0.00270 −0.00084
41 Quetiapine 0.72 0.0098 −0.410 −0.00107 −0.00037
42 Chlorprotixen 0.57 0.0200 −0.122 −0.00039 −0.00013
43 Perazine 0.44 0.0126 0.105 0.00031 0.00011
44 Trifluoperazine 0.44 0.0126 0.105 0.00026 0.00010
45 Thioridazine 0.52 0.0091 −0.035 −0.00009 −0.00003
46 Fluconazole 0.68 0.0095 −0.327 −0.00107 −0.00042
47 Tolperisone 0.75 0.0369 −0.477 −0.00194 −0.00059
48 Fenspiride 0.80 0.0178 −0.602 −0.00231 −0.00076
49 Pizotifen 0.55 0.0175 −0.087 −0.00029 −0.00010
50 Cyproheptadine 0.62 0.1914 −0.213 −0.00074 −0.00024
51 Clozapine 0.68 0.0220 −0.327 −0.00100 −0.00035
52 Tiapride 0.81 0.0096 −0.630 −0.00192 −0.00064
53 Olanzapine 0.60 0.0102 −0.176 −0.00056 −0.00020
54 Betahistine 0.72 0.0289 −0.410 −0.00301 −0.00079
55 Dexketoprofen 0.61 0.0112 −0.194 −0.00076 −0.00025
56 Caffeine 0.66 0.0123 −0.288 −0.00148 −0.00050
57 Hymecromone 0.73 0.0157 −0.432 −0.00245 −0.00083
58 Ketotifen 0.70 0.0144 −0.368 −0.00119 −0.00042
59 Clemastine 0.45 0.0361 0.087 0.00025 0.00009
60 Salicylic acid 0.70 0.0122 −0.368 −0.00266 −0.00088
61 Indomethacin 0.46 0.0066 −0.069 0.000195 0.00007
62 Piroxicam 0.50 0.0046 0 0 0 2.598 −3.193
63 Naproxen 0.59 0.0127 −0.158 −0.00069 −0.00022