Table 3.

Relationships between the expression of 20 CRC study genes and age and sex.

Gene Symbol	Fold Change of Age			Fold Change of Sex
	<50	≥50	p-Value	Male	Female	p-Value
VANGL1	4.910 ± 7.56	7.155 ± 10.54	0.44	5.706 ± 9.02	6.972 ± 10.08	0.36
IL2RA	0.603 ± 0.640	1.509 ± 1.83	0.02	1.148 ± 1.61	1.098 ± 1.37	0.93
IL2RB	0.699 ± 1.10	0.635 ± 1.24	0.88	0.870 ± 1.37	0.351 ± 0.71	0.02
TGFβ	1.056 ± 1.61	1.285 ± 2.02	0.79	1.308 ± 2.14	1.010 ± 1.34	0.90
SMAD2	1.313 ± 2.20	0.855 ± 1.45	0.74	0.942 ± 1.64	1.205 ± 2.06	0.30
SMAD4	2.157 ± 2.36	2.425 ± 2.21	0.41	2.417 ± 2.20	2.157 ± 2.37	0.34
CD44	0.596 ± 0.814	0.537 ± 0.87	0.44	0.478 ± 0.85	0.687 ± 0.82	0.10
CD133	0.832 ± 1.77	1.329 ± 2.83	0.62	0.870 ± 2.43	1.495 ± 2.44	0.07
HES1	2.830 ± 3.52	2.134 ± 3.28	0.36	2.685 ± 3.39	0.955 ± 3.38	0.44
NOTCH1	1.088 ± 2.18	0.953 ± 2.22	0.58	0.795 ± 2.36	1.332 ± 1.89	0.02
LEF1	1.178 ± 1.80	1.038 ± 1.19	0.58	0.988 ± 1.14	1.260 ± 1.86	0.86
MTA1	1.045 ± 1.01	1.012 ± 0.98	0.85	0.947 ± 0.93	1.144 ± 1.06	0.37
EGFR	2.272 ± 2.60	2.937 ± 4.65	0.75	2.439 ± 3.43	2.986 ± 4.58	0.87
MAP2K1	1.722 ± 2.47	1.235 ± 2.23	0.02	1.495 ± 2.65	1.355 ± 1.78	0.49
FOLH1	0.797 ± 0.70	0.814 ± 0.91	0.65	0.809 ± 0.85	0.804 ± 0.81	0.78
BUB1	0.656 ± 1.65	0.610 ± 1.46	0.18	0.731 ± 1.53	0.476 ± 1.56	0.27
RHOA	0.510 ± 0.621	0.562 ± 1.19	0.11	0.625 ± 1.11	0.414 ± 0.75	0.50
PCSK7	6.590 ± 7.74	3.069 ± 4.48	0.19	4.196 ± 5.12	5.076 ± 6.02	0.42
PITX2	0.976 ± 2.00	0.663 ± 1.13	0.57	0.720 ± 1.13	0.906 ± 2.05	0.58
ANXA3	3.533 ± 4.70	4.399 ± 6.65	0.60	4.298 ± 6.06	3.641 ± 5.71	0.12