Figure 3.

(A) Chemiluminescence resonance energy transfer (CRET)-induced sensing of ATP through the ATP-induced assembly of a supramolecular hemin/G-quadruplex-ATP aptamer/ATP complex on a semiconductor CdSe/ZnS quantum dot (QD). The hemin/G-quadruplex catalyzed oxidation of luminol in the presence of H₂O₂ yields chemiluminescence that results in the CRET process to the QDs and in the luminescence of the QDs. (B) CRET-induced luminescence spectra of the QDs, λem = 620 nm, in the presence of different concentrations of ATP: a = 0 μM; b = 0.125 μM; c = 1.25 μM; d = 5 μM; e = 12.5 μM; f = 50 μM; g = 100 μM. (C) Derived calibration curve for the CRET-induced analysis of ATP by the nucleic acid/QD hybrid. Reproduced with permission from ref. [92]. Copyright 2011 American Chemical Society. Arrows: the arrows correspond to typical excitation arrows.