Figure 1.

Linear skin lesions in LSDMCA2 patients. (A,B) Case-2. She had asymmetric face with limited eyelid closure, linear skin defects on face and neck, which became less obvious with age ((A): age 1^10/12 years; (B): age 7 years). (C) Pedigree of Case-3. Parents are asymptomatic and unrelated. Three pregnancies ended with abortions. (D–H) Photographs of Case-3 (II.4) and her mother (I.2). Individual I.2, presented with linear skin defects, which healed with scarring (arrows) (D,E). Individual II.4 had facial dysmorphism with telecanthus, long upslanting palpebral fissures, short nose, mild retrognathia, and posteriorly rotated ears (G). Linear and patchy erythrodermia on cheeks and neck, which were more pronounced at birth (F) compared to the age of 5 years (H). Hollow circles and squares indicate asyntomatic females and males, respectively. Solid circles indicate affected females. Small solid circles indicate aborted fetuses. Figure from [3] used with permission.