Figure 2.

Schematic representations of lipin pathway and signaling. PA—phosphatidic acid; DAG—diacylglycerol; TAG—triacylglycerol; PE—phosphatidylethanolamine; PC—phosphatidylcholine; PI—phosphatidylinositol; PG—phosphatidylglycerol; CL—cardiolipin; CDP-DAG—cytidine diphosphate diacylglycerol; PS—phosphatidylserine; AKT—protein kinase B; PI3K—phosphoInositide 3-kinase; mTORC1—mitogen-activated protein kinase complex 1; nSREBP—nuclear Sterol regulatory element-binding protein; NE—nuclear envelope; ER- endoplasmic reticulum; PPARα/γ—peroxisome proliferation-activated receptor α/γ; PGC-1α—peroxisome proliferator-activated receptor gamma coactivator 1-alpha [12,72,73,76].