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. 2021 Feb 14;9(2):384. doi: 10.3390/microorganisms9020384

Figure 3.

Figure 3

Persister cells killing by chemicals. For panels A–C, chemicals were used at 5 × MIC concentration in NBY medium. (A) Cisplatin (250 µg/mL); (B) mitomycin C (2.5 µg/mL) and (C) copper (800 µg/mL). (D) To compare the efficiency of copper versus cisplatin to kill persisters, bacterial suspensions of persisters were treated with 0, 0.5 or 1 × MIC of cisplatin and copper (1 × MIC copper = 160 µg/mL; 1 × MIC cisplatin = 50 µg/mL). After 30 min and 60 min incubations, samples were taken for CFU counting.