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. 2021 Feb 19;4(5):e202000974. doi: 10.26508/lsa.202000974

Figure S5. Transcription factor-induced BT+AG+ cells differentiate into oogonia/gonocytes in xrOvaries.

Figure S5.

Heat map representation of the expression of the 453 genes (the cluster 1–5 genes) characterizing the in vitro oogonia/gonocyte differentiation process reported in reference 10 in the GATA3/SOX17/TFAP2C-derived d6ag77 BT+AG+ cells and the parent clone-derived bone morphogenetic protein–induced d6ag77 BT+AG+ cells, in comparison with those in the relevant cell types in reference 10 and in human fetal germ cells reported in reference 47, as indicated. Representative genes are annotated, and gene ontology-term enrichments in each cluster and key genes are listed. ag, aggregation culture days; VT: DDX4 (also known as VASA)-tdTomato; hGC, human germ cells; M, male; F, female; W, developmental week. Numbers following the indications of cellular states denote replicate numbers. The color coding is as indicated.