Figure S5. Nuclear DNA double-strand break and perinuclear glycine–alanine foci were not augmented before emergence of axonal organelle trafficking defects in C9ORF72 spinal MNs on D21.

Image gallery on D21, corresponding to D80 in Fig 6. (For quantification of nuclear 53BP1 [in white] and perinuclear glycine–alanine [in green] foci [arrowhead], refer to Fig 6B and C.) Scale bars = 10 μm.