Table 3.
Functional imaging studies—sample characteristics.
| Study | Study Design | Sybtype | Males(%) | Mean Age (Years) | Age Range (Years) | Mean BMI (Kg/m2) | Duration of Follow-up (Months) | 2nd Imaging Participation | 2nd Mean BMI (Kg/m2) | Measure Adapted for 2nd Imaging | Criteria for Diagnosis | Duration of Illness (Months) | Patients under Medication (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SPECT | |||||||||||||
| Kojima (2005) | Cross-sectional (longitudinal) | AN-R: 12 HC: 11 |
0 | 18.6 | 15.1–22.1 | 12.5 | 3.46 | 100% | 15.6 | Weight gain | DSM-IV | Not mentioned | Not mentioned |
| Takano (2001) | Cross-sectional | AN-R: 8 AN-BP: 6 HC: 8 |
0 | 21.2 | - | 14.0 | - | - | - | - | DSM-IV | 16.8 | 0 |
| Matsumoto (2006) | Longitudinal | AN-R: 5 AN-BP: 3 HC: 8 |
0 | 18.5 | 12.3–24 | 12.9 | 6 | 100% | 18.8 | Weight normalization. | DSM-IV | 28 | 0 |
| Komatsu (2010) | Longitudinal | AN: 10 HC: 10 |
0 | 13.2 | 11.0–14.3 | 13.1 | 3 | 100% | 16.6 | Weight gain | DSM-IV | Early onset | 0 |
| fMRI | - | ||||||||||||
| S. Gaudio (2015) | Cross-sectional | AN-R: 16 HC:16 |
0 | 15.8 | 13–18 | 16.2 | - | - | - | - | DSM-IV TR | 4 | 0 |
| I. Boehm (2014) | Cross-sectional | AN-R: 33 AN-BP: 2 HC: 35 |
0 | 16.1 | 12–23 | 14.8 | - | - | - | DSM-IV | 18.9 | 0 | |
| F. Amianto (2013) | Cross-sectional | AN-R: 12 HC:10 |
0 | 20.0 | 16–24 | 16.3 | - | - | - | - | DSM-IV | 11.5 | 0 |
| S. Gaudio (2018) | Cross-sectional | AN-R: 15 HC:15 |
0 | 15.7 | 13–18 | 16.1 | - | - | - | DSM-IV TR | 4 | 0 | |
| D. Geisler (2015) | Cross-sectional | AN: 35 HC:35 |
0 | 16.1 | 12–23 | 14.8 | - | - | - | - | DSM-IV | 18.9 | 0 |
| S. Ehrlich (2015) | Cross-sectional | AN-R: 33 AN-BP: 2 HC: 35 |
0 | 16.1 | 12–23 | 14.8 | - | - | - | - | DSM-IV | 18.9 | 0 |