Figure 2.

Similar regulators identified for SAM subnetworks generated from Yadav et al. and Tian et al. In total, 16 of the top 25 regulators are shared between the two SAM subnetworks (A), though they share only <20% of input DEG genes (B). The rank (C) and weight sum (D) of the two SAM subnetworks are strongly correlated (R² = 0.9212 and 0.8875, respectively). By contrast, the correlation of regulator ranks between the RAM subnetwork (generated from Nawy et al.) with either the SAM subnetwork generated using Yadav et al. (E) or Tian et al. (F) is much weaker (R² = 0.1292 and 0.1451, respectively).