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. 2021 Feb 14;22(4):1907. doi: 10.3390/ijms22041907

Table 3.

Antiproliferative activity of the lead compounds and paclitaxel against several human ovarian tumor cell lines.

Antiproliferative Activity IC50 (nM)
Compound SKOV3 IGROV-1 A2780 OVCAR-8 OVCAR-3
38 46 248 68 74 31
42 7 400 42 37 72
45 48 492 104 48 58
Paclitaxel 1 81 39 3 6 17

1 IC50 values against A2780, OVCAR-8, and OVCAR-3 cell lines from Bicaku, E. et al. evaluation [14].