Table 1.
Socio-demographic and clinical characteristics comparison (stage III/IV).
| Covariates | PDT (+Radiation + Chemo) n = 147, n (%) |
Radiation + Chemo n = 227,629, n (%) |
Radiation n = 106,667, n (%) |
Chemo n = 122,193n (%) |
p Value |
|---|---|---|---|---|---|
| Mean age (std) | 65.4 (8.9) | 63.6 (10.3) | 68.3 (11.1) | 66.3 (10.9) | <0.0001 |
| Male gender | 92 (62.6) | 128,376 (56.4) | 60,373 (56.6) | 66,123 (54.1) | <0.0001 |
| Race | <0.0001 | ||||
| White | 117 (79.6) | 189,487 (83.2) | 87,967 (82.5) | 100,119 (81.9) | |
| African American and other | 28 (20.4) | 381,42 (16.8) | 187,00 (17.5) | 22,074 (18.1) | |
| Insurance status | |||||
| Not Insured/Other | 11 (6.4) | 15,261 (6.7) | 8082 (7.6) | 6523 (5.3) | <0.0001 |
| Private/MCO | 44 (30.3) | 84,061 (36.9) | 24,489 (22.9) | 39,924 (32.7) | |
| Medicaid/Medicare | 92 (63.5) | 128,307 (5642) | 74,096 (69.5) | 75,746 (61.9) | |
| Education * | <0.0001 | ||||
| ≥29% | 31 (21.1) | 43,236 (19.1) | 22,303 (21.0) | 23,007 (18.9) | |
| 20% to 28.9% | 35 (23.8) | 59,710 (26.3) | 28,134 (26.5) | 29,909 (24.6) | |
| 14% to 19.9% | 38 (25.9) | 56,024 (24.7) | 25,507 (24.0) | 29,535 (24.3) | |
| <14% | 43 (29.3) | 67,774 (29.9) | 30,284 (28.5) | 39,223 (232.2) | |
| Income | <0.0001 | ||||
| Less than USD 38,000 | 19 (12.9) | 36,425 (16.1) | 19,201 (18.1) | 18,607 (15.3) | |
| USD 38,000–USD 47,999 | 27 (18.4) | 45,079 (19.9) | 21,963 (20.7) | 22,900 (18.8) | |
| USD 48,000–USD 62,999 | 45 (30.6) | 65,545 (28.9) | 30,556 (28.8) | 34,021 (27.9) | |
| USD 63,000+ | 56 (38.1) | 79,632 (35.1) | 34,432 (32.4) | 46,126 (37.9) | |
| Geographic area | 0.3093 | ||||
| Metro | 115 (78.2) | 179,826 (79.0) | 84,350 (79.1) | 99,092 (81.1) | |
| Non metro | 32 (21.8) | 53,803 (21.0) | 22,317(20.9) | 23,101 (18.9) | |
| Cancer program | <0.0001 | ||||
| Community /Comprehensive | 59 (40.1) | 124,324 (55.2) | 56,788 (53.5) | 65,351 (54.1) | |
| Academic/Research | 61 (41.5) | 70,605 (31.3) | 34,823 (32.8) | 40,960 (33.9) | |
| Integrated Network | 27 (18.4) | 30,438 (13.5) | 14,627 (13.8) | 14,555 (12.0) | |
| Charlson/Deyo score | <0.0001 | ||||
| 0 | 74 (50.3) | 151,490 (66.6) | 63,469 (59.9) | 78,834 (64.5) | |
| 1 | 46 (31.3) | 53,722 (23.6) | 27,624 (25.9) | 29,722 (24.3) | |
| ≥2 | 27 (18.4) | 22,417 (9.9) | 15,574 (14.5) | 13,637 (11.1) | |
| Stage | <0.0001 | ||||
| III | 89 (60.5) | 100,507 (44.2) | 23,185 (21.7) | 24,503 (20.1) | |
| IV | 58 (39.5) | 127,122 (55.9) | 83,482 (78.3) | 97,690 (79.9) | |
| Histology | 40 (27.2) | 95,874 (42.1) | 43,011 (40.3) | 63,637 (52.1) | <0.0001 |
| Adeno Carcinoma | 19 (12.9) | 42,921 (18.9) | 22,503 (21.1) | 19.905 (16.3) | |
| Non-Small Cell Squamous Cell | 74 (50.3) | 61,996 (27.2) | 26,066 (24.4) | 20,936 (17.1) | |
| Other | 14 (9.6) | 26,838 (11.8) | 15,087 (14.2) | 17,715 (14.5) | |
| Mortality | n = 130 | n = 209,390 | n = 98,534 | ||
| Overall | 118 (90.8) | 183,956 (87.9) | 94,239 (95.6) | 103,265 (91.3) | <0.0001 |
| Mean time to death in months (std) | 18.6 (23.9) | 18.0 (21.1) | 7.3 (12.6) | 14.7 (16.9) | <0.0001 |
* Proportion of adults in the patient’s zip code who did not graduate from high school.