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. 2021 Feb 11;13(2):599. doi: 10.3390/nu13020599

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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EGCG treatment improved the lipid profile in NAFLD mice. Diet-induced NAFLD mice were randomly divided into three treatment groups: PBS, EGCG-25, and EGCG-50, and treated for 8 weeks. Mice were examined 4 months following commencement of treatment. Hepatic triglyceride (TG) and high-density lipoprotein (HDL) levels in the EGCG-treated group was not altered compared with pretreatment levels. The TC level of the PBS group was significantly higher than that of the CTL (* p < 0.05, ** p < 0.01 vs. CTL of the same group/time-point; and #, p < 0.01 vs. EGCG-25 and EGCG 50 at the same group/time point). However, no differences were detected in the levels of low-density lipoprotein ( LDL).