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Characterization of TME with IHC markers. (a) CD45 expression: hematopoietic cells (both lymphocytes and macrophages). (b) CD163 expression: M2 macrophages. (c) PDL-1 expression: presence of positive tumor cells in the perivascular space. (d) CD34 expression: endothelial cells. Representative images captured from OSU Tissue Archives.
