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. 2021 Feb 11;14(2):144. doi: 10.3390/ph14020144

Scheme 1.

Scheme 1

Synthesis of the target compounds 10a–j. Reagents and conditions: (a) NaOH, dil. EtOH, rt; (b) NaOH, abs. EtOH; (c) DMF, reflux; (d) SOCl2, reflux, dry benzene, distillation; (e) abs. dichloromethane, TEA, rt.