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. 2021 Feb 13;11(2):121. doi: 10.3390/jpm11020121

Table 2.

Volume of each region of interest (ROI).

Healthy Subjects (HS) Patients with Bipolar Disorder (BD) Patients with Schizophrenia (SZ) df F p
Intracranial Volume (mL) 1380 ± 128 1422 ± 136 1418 ± 157 2, 72 0.79 0.46
Left Hippocampus
Absolute (mL) 2.91 ± 0.22 2.92 ± 0.24 2.72 ± 0.24
Relative (%) 0.211 ± 0.015 0.206 ± 0.022 0.193 ± 0.018 2, 72 7.47 0.001 *
Right Hippocampus
Absolute (mL) 2.95 ± 0.29 2.86 ± 0.20 2.67 ± 0.28
Relative (%) 0.214 ± 0.014 0.202 ± 0.020 0.189 ± 0.017 2, 72 15.06 <0.0001
Left Amygdala
Absolute (mL) 1.26 ± 0.17 1.28 ± 0.14 1.24 ± 0.16
Relative (%) 0.091 ± 0.009 0.091 ± 0.012 0.087 ± 0.009 2, 72 1.01 0.37
Right Amygdala
Absolute (mL) 1.25 ± 0.20 1.31 ± 0.14 1.26 ± 0.17
Relative (%) 0.091 ± 0.010 0.093 ± 0.012 0.089 ± 0.008 2, 72 0.78 0.46
Left Heschl’s gyrus
Absolute (mL) 2.03 ± 0.50 2.02 ± 0.53 1.95 ± 0.59
Relative (%) 0.147 ± 0.032 0.148 ± 0.039 0.137 ± 0.035 2, 72 0.71 0.50
Right Heschl’s gyrus
Absolute (mL) 1.71 ± 0.48 1.77 ± 0.46 1.75 ± 0.55
Relative (%) 0.123 ± 0.029 0.125 ± 0.034 0.123 ± 0.034 2, 72 0.03 0.97
Left Planum temporale
Absolute (mL) 2.94 ± 0.60 2.88 ± 0.68 2.79 ± 0.56
Relative (%) 0.213 ± 0.036 0.203 ± 0.046 0.197 ± 0.032 2, 72 1.20 0.31
Right Planum temporale
Absolute (mL) 2.53 ± 0.76 2.56 ± 0.36 2.63 ± 0.65
Relative (%) 0.183 ± 0.050 0.182 ± 0.032 0.186 ± 0.044 2, 72 0.06 0.94

* Post hoc tests indicated that schizophrenia (SZ) was significantly different from bipolar disorder (BD) and healthy subjects (HS) (Tukey’s honestly significant difference test, p < 0.05). Post hoc tests indicated that volumes were significantly different as follows; HS > BD > SZ (Tukey Honestly Significant Difference, p < 0.05).