Table 3.

Justification of the cut-off levels for the admission values of laboratory findings to predict transferring to ICU

No.	Feature	Normal values	Threshold moving technique				Percentile level
			Cut-off	Sensitivity	Specificity	AUC	Cut-off	Sensitivity	Specificity	AUC*
1	WBC (×109/L)	4.0–11.0	45	0.6	0.5	0.5486	7	0.5278	0.75	0.6389
2	Lymphocytes (×109/L)	1–4.8	0.3	0.43	0.62	0.5267	1.24	0.7778	0.75	0.7639
3	Total bilirubin (μmol/L)	3.4–20.5	37	0.54	0.43	0.4880	11.9	0.4861	0.7439	0.6150
4	ALT (U/L)	0–55	435	0.29	0.68	0.4880	43	0.4583	0.7439	0.6011
5	AST (U/L)	5–34	400	0.53	0.46	0.4944	32	0.7639	0.7418	0.7528
6	D-dimer (mg/L)	0.0–0.5	15	0.35	0.7	0.5261	0.7	0.7222	0.7234	0.7228
7	aPTT (s)	28.0–40.0	180	0.57	0.71	0.6413	39.9	0.5139	0.7336	0.6237
8	CK (U/L)	30.0–200.0	4808	0.54	0.63	0.5864	247	0.4028	0.6619	0.5323
9	CRP (mg/L)	0.0–5.0	400	0.6	0.79	0.6921	14.3	0.9306	0.75	0.8403
10	LDH (U/L)	125–243	1778	0.21	0.88	0.5427	246	0.8889	0.6537	0.7713
11	Troponin (ng/mL)	<0.03	11	0.33	0.75	0.5427	0.037	0.2361	0.7172	0.4767
12	Ferritin (ng/mL)	21.8–274.6	14 025	0.35	0.82	0.5824	498	0.6667	0.75	0.7083
13	Fibrinogen (mg/dL)	200–400	3030	0.33	0.89	0.6124	446	0.8611	0.4939	0.6774

*The AUC values marked in bold are higher than the ones displayed in online supplemental figure 3A.

ALT, alanine aminotransferase; aPTT, activated partial thromboplastin time; AST, aspartate aminotransferase; AUC, area under the curve; CK, creatine kinase; CRP, C reactive protein; LDH, lactate dehydrogenase; WBC, white blood cell.