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. 2021 Feb 12;19(2):111. doi: 10.3390/md19020111

Table 2.

The bactericidal activities of extracts from transgenic B. subtilis strains equivalent to the efficacious doses of antibiotic against different pathogens.

Pathogens Strains
C117 a C166 a T1 b T13 b
Promoter
P43 P43 P43 P43
Tandem repeats c
2× CiMAM 2× CiMAM 3× LFB 3× LFB
Plasmid copy number d
1057 349 931 647
S. epidermidis 48 (Amp) 41 (Amp) 154 (Amp) 130 (Amp)
E. tarda 39 (Amp) 37 (Amp) 79 (Amp) 33 (Amp)
V. parahaemolyticus 47 (Tet) 25 (Tet) 30 (Tet) 26 (Tet)
V. natriegens 57 (Tet) NA NA 9 (Tet)

Unit: ng·L−1, a C117 and C166: the transgenic B. subtilis strains harbored pP43-2CiMAM-GFP expression vector used in this study; b T1 and T13: the transgenic B. subtilis strain harbored pP43-6LFB-GFP expression vector published by Lee et al., 2019; c tandem repeats of cDNA encoding CiMAM or LFB (2×: double-repeats; 3×: triple repeats) in the expression vector transmitted stably in the transgenic lines; d An average copy number of plasmids per cell; (Amp) expressed as an equivalent antibacterial potency against Ampicillin; (Tet) expressed as an equivalent antibacterial potency against Tetracycline.