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. 2021 Feb 15;22(4):1918. doi: 10.3390/ijms22041918

Table 1.

Association between C-C motif chemokine ligand 5 (CCL5) and the clinicopathological factors in 111 breast carcinomas.

Clinicopathological Factors CCL5 Status p-Value
Negative (n = 72) Positive (n = 39)
Age * 56 (29–82) 56 (27–87) 0.40
Menopause
Premenopausal 29 12 0.32
Postmenopausal 43 27
Stage
I 41 22 0.56
II 17 12
III 14 5
Pathological T Factor
pT1 48 25 0.79
pT2-4 24 14
Lymph Node Metastasis
Negative 49 26 0.88
Positive 23 13
Histological Grade
1 (well) 32 11 0.0061
2 (intermediate) 31 13
3 (poor) 9 15
ER
Negative 8 13 0.0043
Positive 64 26
PR
Negative 15 20 0.0010
Positive 57 19
HER2
Negative 63 33 0.67
Positive 9 6
Ki67 LI (%) * 9.5 (1–60) 16 (1–49) 0.090
MVD * 24.5 (3–101) 32 (7–106) 0.040
Macrophage infiltration
Low 55 20 0.0070
High 17 19

* Data were presented as median (minimum–max). All other values represent the number of cases. p < 0.05 was considered significant and described in boldface, and 0.05 ≤ p < 0.1 was described in italic. ER: estrogen receptor, HER2: human epidermal growth factor receptor 2, LI: labeling index, MVD: microvessel density and PR: progesterone receptor.