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. 2021 Feb 22:1–14. doi: 10.1080/08830185.2021.1884248

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Figure 2. — IMMs are induced to accumulate and produce large quantities of cytokines and chemokines after infection, resulting in the apoptosis of T cells together with a delayed IFN-?/? response. The T cell apoptosis further blocks the clearance of viruses and induces proinflammatory cytokine release, which may further aggravate a cytokine storm.