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. 2021 Mar 1;147(3):e2020017830. doi: 10.1542/peds.2020-017830

TABLE 2.

Results of Multivariable Linear Regression Models

Outcome and Group Comparison Mean Difference P Lower 95% CI Upper 95% CI
Length of hospital stay
 Morphine versus M + P −7.22 <.0001 −9.70 −4.75
 Morphine versus M + C −17.48 <.0001 −19.59 −15.38
 M + P versus M + C −10.26 <.0001 −13.21 −7.31
Length of morphine treatment
 Morphine versus M + P −6.19 <.0001 −8.49 −3.88
 Morphine versus M + C −13.70 <.0001 −15.67 −11.72
 M + P versus M + C −7.51 <.0001 −10.27 −4.75
Peak morphine dose mg/kg
 Morphine versus M + P −0.017 <.0001 −0.026 −0.008
 Morphine versus M + C −0.008 .037 −0.015 −0.0005
 M + P versus M + C 0.010 .072 −0.0008 0.019

Morphine; M + P; M + C; covariates included race and ethnicity, infant sex, maternal polysubstance use; type of maternal opioid, >1 opioid, and hospital volume.