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. 2021 Mar 1;40:81. doi: 10.1186/s13046-021-01874-1

Fig. 4.

Fig. 4

Application of scRNA-seq to evaluate tumor immune escape. a scRNA-seq is used to detect and screen for neoantigens. b Detection of transcriptional activity at immune checkpoints and evaluation of ICI drug resistance mechanisms by scRNA-seq. c scRNA-seq detection of immune escape caused by MHC mutations. d Identification of TCR sequences within different T cells by scRNA-seq