Table 2.
Gene | RefSeq | Description | FCa | FDRb |
---|---|---|---|---|
Upregulated | ||||
SIM2 | NM_005069.3 | single-minded family bHLH transcription factor 2 | 4.26 | 7.63E-07 |
FAP | NM_001291807.1 | fibroblast activation protein, alpha | 3.34 | 0.00112 |
FUT1 | NM_000148.3 | fucosyltransferase 1 | 3.04 | 0.00017 |
ESM1 | NM_001135604.1 | endothelial cell-specific molecule 1 | 2.98 | 0.00060 |
FABP6 | NM_001040442.1 | fatty acid binding protein 6, ileal | 2.95 | 0.00420 |
COL1A1 | NM_000088.3 | collagen, type I, alpha 1 | 2.75 | 0.00181 |
WNT2 | NM_003391.2 | wingless-type MMTV integration site family member 2 | 2.65 | 0.00601 |
ELN | NM_000501.3 | elastin | 2.22 | 0.00072 |
ETV4 | NM_001079675.2 | ets variant 4 | 2.18 | 0.00060 |
ACAN | NM_001135.3 | aggrecan | 2.12 | 0.00107 |
LARP6 | NM_001286679.1 | La ribonucleoprotein domain family, member 6 | 2.00 | 0.00111 |
FADS1 | NM_013402.4 | fatty acid desaturase | 2.00 | 0.00099 |
SCRN1 | NM_001145513.1 | secernin 1 | 1.97 | 0.00188 |
LY6E | NM_001127213.1 | lymphocyte antigen 6 complex, locus E | 1.95 | 0.00691 |
TCFL5 | NM_006602.2 | transcription factor-like 5 (basic helix-loop-helix) | 1.91 | 0.00426 |
PROCR | NM_006404.4 | protein C receptor, endothelial | 1.90 | 0.00745 |
FAM150A | NM_001195732.1 | family with sequence similarity 150 member A | 1.87 | 0.00283 |
COL5A2 | NM_000393.3 | collagen, type V, alpha 2 | 1.73 | 0.00601 |
FAM72D | NM_207418.2 | family with sequence similarity 72 member D | 1.62 | 0.00262 |
SPARC | NM_003118.3 | secreted protein, acidic, cysteine-rich (osteonectin) | 1.62 | 0.00420 |
PARVB | NM_001003828.2 | parvin, beta | 1.56 | 0.01610 |
VEGFA | NM_001025366.2 | vascular endothelial growth factor A | 1.46 | 0.00123 |
UBE2C | NM_001281741.1 | ubiquitin-conjugating enzyme | 1.45 | 0.00060 |
AUNIP | NM_001287490.1 | aurora kinase A and ninein interacting protein | 1.35 | 0.00177 |
GK | NM_000167.5 | glycerol kinase | 1.26 | 0.00437 |
LRP8 | NM_001018054.2 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 1.15 | 0.01137 |
DIAPH3 | NM_001042517.1 | diaphanous-related formin 3 | 1.11 | 0.00178 |
FAM162B | NM_001085480.2 | family with sequence similarity 162 member B | 1.05 | 0.04851 |
CENPJ | NM_018451.4 | centromere protein J | 1.04 | 0.00243 |
Downregulated | ||||
CLCA1 | NM_001285.3 | chloride channel accessory 1 | −7.97 | 0.00155 |
HEPACAM2 | NM_001039372.2 | HEPACAM family member 2 | −4.05 | 0.00131 |
B3GNT6 | NM_138706.4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 | −4.03 | 0.00177 |
BEST2 | NM_017682.2 | bestrophin 2 | −3.86 | 0.00099 |
L1TD1 | NM_001164835.1 | LINE-1 type transposase domain containing 1 | −3.52 | 0.02738 |
ADH1A | NM_000667.3 | alcohol dehydrogenase 1A (class I) alpha polypeptide | −3.48 | 0.00852 |
ADH1C | NM_000669.4 | alcohol dehydrogenase 1C (class I), gamma polypeptide | −3.39 | 0.00776 |
GALNT8 | NM_017417.1 | polypeptide N-acetylgalactosaminyltransferase 8 | −3.24 | 0.00084 |
SPTLC3 | NM_018327.2 | serine palmitoyltransferase, long chain base subunit 3 | −2.99 | 0.00244 |
SPINK2 | NM_001271718.1 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | −2.49 | 0.01166 |
ATOH8 | NM_153778.3 | atonal homolog 8 | −2.32 | 0.00643 |
KCNMA1 | NM_001014797.2 | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | −2.27 | 0.00060 |
NEURL | NM_004210.4 | neuralized E3 ubiquitin protein ligase 1 | −2.19 | 0.00109 |
PIGR | NM_002644.3 | polymeric immunoglobulin receptor | −2.14 | 0.01272 |
MFSD4 | NM_181644.4 | major facilitator superfamily domain containing 4 | −2.11 | 0.00201 |
ARHGAP44 | NM_014859.4 | Rho GTPase activating protein 44 | −2.06 | 0.00060 |
SERTAD4 | NM_019605.3 | SERTA domain containing 4 | −1.82 | 0.00072 |
PLA2G10 | NM_003561.1 | phospholipase A2, group X | −1.73 | 0.04438 |
NEDD4L | NM_001144964.1 | eural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | −1.61 | 0.00123 |
ACADVL | NM_000018.3 | acyl-CoA dehydrogenase, very long chain | −1.20 | 0.00099 |
PID1 | NM_001100818.1 | phosphotyrosine interaction domain containing 1 | −1.19 | 0.01212 |
aFC (log2 fold change); bFDR (false discovery rate). The genes in bold are the same ones selected in Table 1 for validation by RT-qPCR