Figure 6.

Involvement of AT₁R in the antioxidant effect of VRP, LKY, VRY, and V-F in Ang II-stimulated VSMCs. Peptides (50 μM) were incubated with cells for (A) 1 h, with 50 μM AT₁R antagonist (losartan), or (B) 24 h, followed by adding 50 μM losartan for 1 h, before the addition of Ang II (1 μM) for 30 min. Data were expressed as means ± SEM of four independent experiments and normalized to the Ang II-treated group. ## p < 0.01, * p < 0.05, ** p < 0.01, as compared to the Ang II-treated group. Untr, untreated group.