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. 2021 Mar;31(3):349–358. doi: 10.1101/gr.269381.120

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© 2021 Yang et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see https://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 1. — Global inflation of test statistics from linear regressions between blood-derived mtDNA-CN and gene expression in blood. After stratification by gene category, protein-coding genes have the most inflation, suggesting that mtDNA-CN is strongly associated with genes that code for proteins.