Table 5.
Multiple linear regression analysis of the effects of sleep parameters on metabolic variables in subjects without OSA.
| Model 1 | Model 2 | |||||||
|---|---|---|---|---|---|---|---|---|
| Outcome | Predictor | β | Standard error | p-value | Predictor | β | Standard error | p-value |
| BMI (kg/m2) | (-) | (-) | (-) | (-) | (-) | (-) | (-) | (-) |
| Glucose (mmol/L) | (-) | (-) | (-) | (-) | (-) | (-) | (-) | (-) |
| Insulin (μU/mL) | REM/TST (%) | −0.074 | 0.025 | 0.003 | REM/TST (%) | −0.071 | 0.025 | 0.005 |
| SWS/TST (%) | 0.035 | 0.017 | 0.038 | SWS/TST (%) | 0.035 | 0.017 | 0.038 | |
| SBP (mmHg) | REM/TST (%) | 0.156 | 0.059 | 0.008 | REM/TST (%) | 0.164 | 0.059 | 0.005 |
| DBP (mmHg) | REM/TST (%) | 0.109 | 0.044 | 0.014 | REM/TST (%) | 0.110 | 0.044 | 0.013 |
| TC (mmol/L) | MAI | 0.005 | 0.002 | 0.012 | MAI | 0.005 | 0.002 | 0.036 |
| TG (mmol/L) | (-) | (-) | (-) | (-) | (-) | (-) | (-) | (-) |
| HDL (mmol/L) | TST | 0.01 | 0.01 | <0.001 | TST | 0.000 | 0.000 | 0.001 |
| LDL (mmol/L) | MAI | 0.007 | 0.002 | <0.001 | MAI | 0.006 | 0.002 | 0.001 |
Model 1 was adjusted for age, sex, smoking status, and alcohol use; model 2 was adjusted for variables in model 1 and additional AHI and ODI.
OSA, obstructive sleep apnea; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TST, total sleep time; REM, rapid eye movement; MAI, microarousal index.