Figure 1. Discovery of subhistology EMT groups using SUV_max and RNA-seq.

(A) Pearson correlation of SUV_max with representative EMT genes. (B) Hierarchical clustering using EMT-correlated genes and histology identified 3 major molecular groups: squamous epithelial, squamous mesenchymal, and adenocarcinoma. Adenosquamous (n = 2) and small cell (n = 2) samples were also present in the cohort (n = 67). (C) Squamous mesenchymal patients showed inferior recurrence-free survival compared with squamous epithelial (log rank test, P = 0.045).