Skip to main content
. 2021 Mar 1;131(5):e139232. doi: 10.1172/JCI139232

Figure 2. Validation of subhistology EMT groups using TCGA data.

Figure 2

(A) Hierarchical clustering validated 3 major molecular groups, namely squamous epithelial, squamous mesenchymal, and adenocarcinoma. In addition, adenosquamous samples (n = 5) are shown in purple. n = 304. (B) BCV analysis using EMT-correlated genes confirmed the 3 major molecular groups. One outlier adenocarcinoma sample is excluded in the BCV analysis. Adenosquamous samples are clustered close to adenocarcinoma samples. (C) Comparison of HPV genotype-specific mesenchymal gene expression with 2-proportions tests.