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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: ACS Chem Biol. 2019 Dec 10;15(1):205–216. doi: 10.1021/acschembio.9b00785

Fig. 2.

Fig. 2

Structural features of the JIIIabc four-way junction. (a) Overall architecture of the JIIIabc based on the crystal structure of JIIIabc – HCV2 complex. (b) Secondary structure of the JIIIabc derived from the crystal structure. The dotted lines represent the tertiary interactions. (c) Structural features of the JIIIabc four-way junction. (d-i) Specific interactions between the nucleotides organizing the four-way junction. The dashed lines reflect heteroatoms within hydrogen bonding distance. Blue mesh represents the 2|Fo| - |Fc| electron density map at 1σ contour level and carve radius 1.8 Å. All figures and the labels are colored analogously for facile comparison.