. 2021 Feb 16;13(4):820. doi: 10.3390/cancers13040820

Table 3.

Molecular classification of Small cell lung carcinoma (SCLC) subsets.

SCLC Subtype	Markers	Characteristics
SCLC-A	ASCL1	Pure SCLC histology; NE-markers^high/TTF-1^high/DLL3^high
SCLC-N	NEUROD1	Enrichment in combined SCLC histology; NE-markers^high/TTF-1^high/DLL3^high
SCLC-P	POU2F3	Low or absent expression of ASCL1 and NEUROD1, NE-markers^low/TTF-1^low/DLL3^low
SCLC-Y	YAP1	Low or absent expression of ASCL1 and NEUROD1; RB1^wt
SCLC-I	Inflamed Gene signature	Low expression of ASCL1, NEUROD1, and POU2F3