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Fibrinogen is associated with central nervous system (CNS) lymphoma. Microscopy of tissue sections from postmortem brains of human patients with CNS lymphoma, stained with antibodies to fibrinogen, laminin (basal membrane), CD20 (B cell), and ionized calcium-binding adaptor protein-1 (Iba-1; microglia), showing fibrinogen surrounding a CD20+ B-cell lymphoma around leaky blood vessels. Scale bars: 100 μm (A); 80 μm (B and C).
