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. 2021 Feb 27;10(1):317–330. doi: 10.1080/22221751.2021.1888660

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Structures of BLF, HLF, and the docking model of heparin dp4 with bovine lactoferricin. (A) Surface electrostatics of BLF (PDB: 1BLF). (B) Surface electrostatics of HLF (PDB: 1LFI). (C) Sequence alignment of the positively charged N-terminal domain of BLF and HLF. (D) Docking model of heparin dp4 with bovine lactoferricin (PDB: 1LFC). The heparin dp4 structure was from PDB 5E9C. (E) Surface view of the docking model of heparin dp4 with bovine lactoferricin. Docking was performed using AutoDock Vina and figures were generated using PyMOL. (F) Proposed antiviral mechanism of LF. The figure was created with BioRender.com.