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. 2020 Oct 5;14:17–21. doi: 10.1016/j.jcot.2020.10.002

Table 6.

Studies of self-reported metal hypersensitivity in orthopedic surgery.

Implant N of patients Prevalence of self-reported cutaneous metal sensitivity Conclusion
Bloemke et al., 2015 (20) TKA 139 %14 Surgeons who decided to choose an individualized approach to implant selection could expect to use a specialized implant in approximately 15% of patients.
Nam et al., 2016 (31) THA
TKA
906
598
%2.3
4.1%
Patient-reported metal allergy is associated with decreased functional outcomes after TKA and decreased mental health scores after THA
Walker et al., 2019 (15) UKA 1737 4.7% Functional outcome and survivorship are on a high-level equivalent to those reported for UKA in patients without a history of metal hypersensitivity.
Schultzel et al., 2020 (10) NA 840 4.9% Greater awareness of a history to hypersensitivity may prevent patient exposure to implants containing metals that may cause hypersensitivity.
Kennon et al., 2020 (33) Shoulder Arthroplasty 52 82.6% Shoulder arthroplasty in patients with self-reported metal allergy provides satisfactory pain relief and improved range of motion with low revision rates.
Atilla et al. UKA 128 10.2% The functional outcomes of patients who underwent UKA using a standard alloy did not change between the groups who reported having or not having a history of metal hypersensitivity

TKA: Total Knee Arthroplasty, THA: Total Hip Arthroplasty, UKA: Unikondylar Knee Arthroplasty, NA: Non Available, N:Number.