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T cell Infiltration per se does not define tumor regression. P607 tumor tissue was surgically resected from a metastatic melanoma patient, revealing abundant T cell infiltration by immunoperoxidase labeled anti-CD8 (red) and alkaline phosphatase labeled anti-CD3 staining (blue). Cytokine analysis of tumor homogenates can reveal the prevailing immune response to better understand tumor expansion despite heavy T cell presence.
