Skip to main content
. 2021 Feb 16;10(2):298. doi: 10.3390/antiox10020298

Figure 5.

Figure 5

Modulating effects of DK and ECE on endothelial cell dysfunction in the aorta of SHRs. (A,B) The peNOS/eNOS expression level in aorta tissue was decreased following SHR/water and increased following ECE or DK treatment. (C) The nitrate/nitrite in aorta tissue was increased following SHR/water and decreased following ECE or DK treatment. (D) The relative NDAPH/NADP+ ratio in aorta tissue was increased following SHR/water and decreased following ECE or DK treatment. (E,F) The systolic BP (E), diastolic BP (F), and mean BP (G) were increased following SHR/water and decreased following ECE or DK treatment. For each of the 6 groups, n = 5. Scale bar = 100 µm. **, p < 0.01 vs. WKY/water; $, p < 0.05 and $$, p < 0.01, vs. SHR/water; #, p < 0.05 and ##, p < 0.01, vs. SHR/ECE150 (Mann–Whitney U test). BP, blood pressure; DAB, 3,3-diaminobenzidine; DK, dieckol; ECE, Ecklonia cava extract; peNOS, phosphorylated endothelial nitric oxide synthase; SHR, spontaneously hypertensive rat; WKY, Wistar Kyoto rat.