Table 1.
The clinical and pathologic characteristics of the enrolled subjects
| Characteristics | Patient | ||||
|---|---|---|---|---|---|
| 1006 | 1007 | 1008 | 1012 | 1013 | |
| Age, yr | 72 | 48 | 50 | 68 | 47 |
| Gender | M | M | M | F | F |
| BMI, kg/m2 | 28 | 33 | 30 | 37 | 50 |
| BP, mm Hg | 188/70 | 144/77 | 129/61 | 101/60 | 176/81 |
| eGFR, ml/min per 1.73 m2 | 22 | 39 | 22 | 23 | 21 |
| ΔeGFR, ml/min per 1.73 m2 | 0.59 | −2.3 | 12.01 | 4.76 | −12.7 |
| UPCR, mg/g | 1400 | 1100 | 800 | 1500 | 5000 |
| ΔUPCR, mg/g | −700 | 130 | 1140 | 320 | 900 |
| UA | |||||
| Epi | 0–2 | 0–10 | 0 | 0–5 | 10–20 |
| WBC | 0–1 | 0–5 | 0–5 | 0–5 | 5–10 |
| RBC | 0–2 | 0–2 | 0–2 | 0 | 2–5 |
| RPS class | 2 | 3 | 2 | 3 | 3 |
| Global sclerosis (%) | 26–50 | 1–25 | 26–50 | 26–50 | 26–50 |
| Interstitial fibrosis (%) | 50 | 80 | 50 | 40 | 60 |
| Mesangial matrix increase | Mod | Severe | Mod | Mod | Severe |
| Interstitial lymphocytes | Mod | Mod | Mild | Mild | Mod |
| Arterial sclerosis | Severe | Mild | Mild | Mod | Severe |
| Foot process effacement (%) | 30 | 70 | 30 | 30 | 50 |
| Avg GBM thickness (nm) | 431 | 491 | 722 | 785 | 1120 |
BMI, body mass index; UPCR, urine protein to creatinine ratio; UA, urinalysis; epi, epithelial cells; WBC, white blood cells; RBC, red blood cells; RPS class, Renal Pathology Society classification; mod: moderate; GBM, glomerular basement membrane.