Table 2.
AKI incidence after PCI by race and baseline eGFR
| AKI Outcomes, n/N (%) | Overall, n=9422 | Race | |||
|---|---|---|---|---|---|
| White, n=7084 | Black, n=1854 | Other, n=484 | P Value | ||
| AKI incidence | 865/9422 (9) | 561/7084 (8) | 258/1854 (14) | 46/484 (10) | <0.001 |
| By baseline eGFR, ml/min per 1.73 m2 | NA | ||||
| ≥90 | 127/2227 (6) | 67/1471 (5) | 52/611 (9) | 8/145 (6) | |
| 60 to <90 | 237/4439 (5) | 158/3472 (5) | 66/750 (9) | 13/217 (6) | |
| 30 to <60 | 358/2396 (15) | 261/1909 (14) | 79/384 (21) | 18/103 (18) | |
| 15 to <30 | 83/248 (34) | 49/180 (27) | 31/56 (55) | 3/12 (25) | |
| <15 | 60/112 (54) | 26/52 (50) | 20/53 (57) | 4/7 (57) | |
| Incidence of other AKI classifications | |||||
| AKI severitya | 0.17 | ||||
| Stage 1 | 662/865 (77) | 441/561 (79) | 188/258 (73) | 33/46 (72) | |
| Stage 2 | 96/865 (11) | 62/561 (11) | 28/258 (11) | 6/46 (13) | |
| Stage 3 | 107/865 (12) | 58/561 (10) | 42/258 (16) | 7/46 (15) | |
| AKI requiring dialysis | 66/865 (8) | 34/561 (6) | 27/258 (11) | 5/46 (11) | 0.05 |
| Contrast-induced nephropathy | 531/9422 (6) | 344/7084 (5) | 160/1854 (9) | 27/484 (6) | <0.001 |
NA means the P value for interaction between race and baseline eGFR on AKI incidence is reported in Table 3.
AKI definitions are based on the KDIGO criteria as follows:
⋅ AKI: a 1.5-fold or greater relative elevation in serum creatinine from a reference value to the highest value within 7 d after PCI. The reference value was the average of all serum creatinine measurements obtained in an outpatient or inpatient setting within 30 d before PCI; and the date of PCI was time zero for the 7-d window.
⋅ AKI severity: stages 1–3 based on the degree of elevation in serum creatinine to the highest value within 14 d post-PCI. Stage 1: 1.5–1.9-fold or 0.3–3.9 mg/dl absolute increase; stage 2: 2–2.9-fold; and stage 3: ≥ three-fold or ≥4 mg/dl absolute increase or initiation of dialysis.
⋅ AKI requiring dialysis: based on dialysis procedure codes obtained from inpatient settings, and defined as receipt versus no receipt of dialysis in a patient with AKI.
⋅ Contrast-induced nephropathy: ≥0.5 mg/dl absolute elevation in serum creatinine from the reference value within 7 d after PCI.
Denominator for AKI severity is number of incident AKI (n=865 overall).