Table 2.

Outcome events and event rate (per yr) overall and by eGFR category

Outcome Events	Overall	eGFR ≥60	eGFR 45 to <60	eGFR <45
All-cause death
Total all-cause deaths, n	9756	4784	3264	1708
Death rate (per 100 person-yr), median (IQR)	2.36 (2.31–2.41)	2.02 (1.97–2.08)	2.29 (2.21–2.37)	4.99 (4.76–5.23)
Noncoronary heart disease deaths, n	7962	3993	2657	1312
Noncoronary heart disease death rate (per 100 person-yr), median (IQR)	1.93 (1.88–1.97)	1.69 (1.64–1.74)	1.86 (1.79–1.93)	3.83 (3.63–4.05)
Composite of major coronary eventsa
Total events, n	5238	2584	1827	827
Event rate (per 100 person-yr), median (IQR)	1.34 (1.30–1.37)	1.15 (1.10–1.19)	1.36 (1.30–1.43)	2.52 (2.36–2.70)
Incident MI events	2802	1381	994	427
Incident MI rate (per 100 person-yr), median (IQR)	0.69 (0.67–0.72)	0.60 (0.57–0.63)	0.72 (0.67–0.76)	1.26 (1.14–1.38)
Fatal coronary heart disease events, n	1794	791	607	396
Fatal coronary heart disease event rate (per 100 person-yr), median (IQR)	0.43 (0.41–0.45)	0.33 (0.31–0.36)	0.43 (0.39–0.46)	1.16 (1.05–1.28)
Revascularization procedures, n	2582	1377	940	265
Procedure event rate (per 100 person-yr), median (IQR)	0.64 (0.62–0.67)	0.60 (0.57–0.63)	0.69 (0.64–0.73)	0.79 (0.69–0.88)
Ischemic stroke
Total ischemic strokes, n	1985	986	682	317
Ischemic stroke event rate (per 100 person-yr), median (IQR)	0.48 (0.46–0.50)	0.42 (0.39–0.45)	0.48 (0.45–0.52)	0.92 (0.82–1.03)
Heart failure
Total heart failure events, n	4473	2168	1520	785
Heart failure event rate (per 100 person-yr), median (IQR)	1.16 (1.12–1.19)	0.97 (0.93–1.01)	1.15 (1.09–1.21)	2.49 (2.32–2.67)

^aDefinite or probable myocardial infarction, definite fatal coronary heart disease, and revascularization procedure including coronary angioplasty or other revascularization procedure.