Figure 1.
Overview of the phenotypic characteristics and underlying mechanisms of thyroid carcinomas. There are five histologic types of thyroid cancers with variably morphological features. Heterogeneous genetic abnormalities and signaling pathway alterations contribute to the phenotypic variations. PTC: papillary thyroid carcinoma; FTC: follicular thyroid carcinoma; HCC: Hürthle cell carcinoma; MTC: medullary thyroid carcinoma; PDTC: poorly differentiated thyroid carcinoma; ATC: anaplastic thyroid carcinoma; HPF: high power microscopic fields; MED12: mediator complex subunit 12; RNA-binding motif 10; EIF1AX: Eukaryotic Translation Initiation Factor 1A X-Linked.