Trends in the prevalence of current smokers among Italian adults aged ≥15 years, overall and by sex. Italy, 1957–2019. APC: Annual Percent Change; CI: confidence interval; JP: Joinpoint.Squares, triangles and dots represent observed prevalence of current smokers overall and among men and women, respectively. Solid, dashed and dotted lines represent the predicted values obtained from the joinpoint regression models overall and among men and women, respectively. Total: 1957–2001: APC = −0.5% (95% CI: −0.7; −0.2); 2001–2013: APC = −2.8% (95% CI: −3.6; −1.9); 2013–2019: APC = +1.7% (95% CI: −0.5; 4). Men: 1957–2015: APC = −1.7% (95% CI: −1.8; −1.6); 2015–2019: APC = +2.6% (95% CI: −4.1; 9.8). Women: 1957–1990: APC = +4.2% (95% CI: 1.1; 7.4); 1990–2019: APC = −1.5% (95% CI: −2.2; −0.8).