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Genetically engineered NF1 minipigs develop neurofibromas [29]. (A) An example of an NF1 minipig harboring two dermal masses on its left side. The mass denoted by the white box is enlarged in B. (B) mass on the flank measured 4.2 cm in diameter. (C) H&E staining of a representative mass showing regions of hypercellularity. (D) Hypercellular regions stain positive for S100β, a marker of Schwann cells.
