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. 2021 Mar 1;36(2):197–211. doi: 10.1007/s10654-021-00728-6

Table 2.

Univariate analysis for predictors of COVID-19 vaccine acceptance among pregnant women and mothers of young children

Univariate analysis for acceptance of COVID-19 vaccine with ≥ 90% efficacy (likely vs. unlikely) Accept for themselves Accept for child/children
Pregnant women N = 5282 Non-pregnant mothers N = 12,562 All mothers N = 17,054
Characteristics Odds ratios 95% CI Odds ratios 95% CI Odds ratios 95% CI
Age (ref: 40–65 years)
 18–24 0.80 0.56, 1.14 0.66 0.55, 0.79 0.58 0.50, 0.66
 25–29 0.88 0.63, 1.23 0.79 0.70, 0.89 0.71 0.64, 0.79
 30–34 0.93 0.66, 1.30 0.94 0.85, 1.05 0.84 0.77, 0.93
 35–39 0.92 0.65, 1.30 0.92 0.83, 1.03 0.86 0.78, 0.95
Married (ref: unmarried) 0.92 0.82, 1.03 1.10 1.01, 1.19 1.03 0.96, 1.10
Number of children (ref: no child)
 One child (used as ref for non-pregnant women only) 0.86 0.76, 0.97 NA NA 0.91 0.81, 1.02
 Two children 0.57 0.47, 0.68 0.79 0.72, 0.86 0.80 0.71, 0.90
 Three or more children 0.43 0.33, 0.55 0.47 0.42, 0.52 0.50 0.45, 0.57
Education (ref: college diploma or equivalent)
 < High school 0.76 0.58, 0.99 0.97 0.82, 1.14 0.88 0.77, 1.00
 High school or GED 1.25 1.03, 1.53 0.90 0.80, 1.02 0.96 0.87, 1.07
 Some college or university 0.93 0.80 1.09 0.85 0.76, 0.95 0.85 0.78, 0.93
 Master's, professional school, doctoral degree 1.26 1.10, 1.44 1.62 1.45, 1.81 1.54 1.41, 1.68
Socioeconomic status (SES)
 Middle class to wealthy (ref: lower middle class to poor) 0.92 0.82, 1.03 1.25 1.16, 1.36 1.14 1.06, 1.21
Essential workers (ref: non-essential workers)
 Physicians 2.26 1.54, 3.32 2.37 1.58, 3.56 2.03 1.52, 2.72
 Nurses 0.71 0.57, 0.88 0.84 0.69, 1.03 0.75 0.65, 0.88
 Other health workers 0.78 0.65, 0.94 0.76 0.64, 0.90 0.78 0.69, 0.89
 Other essential workers (not health sector) 0.83 1.07, 1.23 0.84 0.75, 0.94 0.85 0.78, 0.94
Health status/insurance
 Have health insurance (ref: no health insurance) 0.93 0.81, 1.08 1.12 1.02, 1.22 1.10 1.02, 1.18
 At least 1 underlying condition (ref: no underlying condition) 1.21 1.08, 1.35 1.40 1.29, 1.52 1.39 1.30, 1.49
 Tested positive for COVID-19 (no COVID-19 test/ tested negative) 1.04 0.93, 1.17 1.26 1.15, 1.38 1.19 1.10, 1.28
Negative experiences with COVID-19
 Negatively affected by COVID-19 in any way (ref: not affected) 1.31 1.18, 1.47 1.32 1.22,1.43 1.31 1.23, 1.40
 Suffered complications/disability due to COVID-19 disease (ref: no complications/disability) 1.97 0.85, 4.57 2.47 1.64, 3.74 2.14 1.51, 3.03
 Lost a loved one to COVID-19 (ref: no loss) 2.82 2.03, 3.94 2.55 2.07, 3.13 2.63 2.20, 3.14
 Other non-COVID-19 related health problems (ref: no additional health problems) 1.43 1.21, 1.68 1.37 1.25, 1.50 1.42 1.31, 1.54
 Socially affected by COVID-19/restrictions (ref: not affected) 1.27 1.13, 1.42 1.26 1.17, 1.37 1.26 1.18, 1.34
 Financial/job loss (ref: no loss) 1.16 1.02, 1.31 1.11 1.02, 1.20 1.11 1.04, 1.19
Past acceptance and perceived safety/efficacy of other vaccines
 Routine immunization for children (ref: no) 8.04 6.46, 10.0 21.2 18.1, 24.9 19.2 16.7, 22.0
 Think childhood vaccines are safe (ref: not safe) 30.7 19.8, 47.7 44.6 36.4, 54.6 46.8 38.5, 56.8
 Think childhood vaccines are effective in protecting against diseases (ref: not effective) 40.1 22.5, 71.3 48.1 37.9, 61.0 52.5 41.5, 66.4
 Received flu vaccination last year or could not receive because of cost or availability (ref: did not receive for reasons other than cost or availability) 3.29 2.91, 3.72 5.24 4.81, 5.71 4.62 4.31, 4.95
Confidence in COVID-19 vaccine
 Confident in safety of COVID-19 vaccine post-approval by country's health agencies (ref: not confident) 8.42 7.44, 9.53 40.8 35.1, 47.5 27.8 25.0, 30.8
 Confident in COVID-19 vaccine efficacy post approval by country's health agencies (ref: not confident) 6.68 5.90, 7.56 28.1 24.9, 35.6 19.7 18.1, 21.5
Perceived risk of the virus/precautions
 Likely to get COVID-19 (ref: unlikely) 1.45 1.29, 1.62 2.02 1.86, 2.19 1.80 1.68, 1.92
 Likely for child to be infected with COVID-19 (ref: unlikely) 1.65 1.42, 1.93 1.88 1.73, 2.03 1.87 1.74, 2.00
 Likely to develop severe symptoms if COVID-19 is contracted (ref: unlikely) 2.18 1.95, 2.43 2.97 2.73, 3.23 2.91 2.72, 3.12
 Worried about COVID-19 (ref: not worried) 5.49 4.80, 6.28 12.2 11.1, 13.4 9.99 9.24, 10.8
 Important for country to have vaccine (ref: not important) 24.1 17.7, 32.7 46.4 39.4, 54.7 45.0 38.7, 52.4
 Important for the majority of people in their country getting vaccinated (ref: not important) 28.7 21.3, 38.6 52.0 45.0, 60.2 53.3 46.4, 61.2
 Closely complied with mask guidelines (ref: did not comply) 13.7 9.23, 20.5 30.5 23.9, 39.0 24.9 20.2, 30.6
 Monitoring COVID-19 news on any media once or less per day (ref: never) 3.56 2.88, 4.41 6.27 5.49, 7.17 5.91 5.26, 6.63
Public trust and satisfaction
 Trust in PH agencies (ref: no trust in PH agencies) 4.47 3.97, 5.03 13.2 11.9, 14.6 10.7 9.86, 11.5
 Satisfied with the country's political leadership on COVID-19 control (ref: dissatisfied with political leadership) 1.08 0.96, 1.21 2.63 2.41, 2.89 2.13 1.98, 2.30
 Trust in science (ref: no trust in science) 4.43 3.81, 5.15 7.91 7.21, 8.68 7.23 6.68, 7.83
 Increased trust in science (ref: no increased trust in science) 3.94 3.50, 4.44 9.11 8.21, 10.1 7.42 6.85, 8.04
 Satisfied with health authorities (ref: dissatisfied with health authorities) 1.68 1.50, 1.87 3.66 3.35, 4.01 3.06 2.85, 3.29
 Satisfied with political response (ref: dissatisfied with political response) 1.62 1.44, 1.81 4.00 3.64, 4.40 3.32 3.08, 3.58