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. 2021 Feb 25;13:2009–2024. doi: 10.2147/CMAR.S296038

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© 2021 Cai et al.

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MRPL13 genomic alterations in BC. (A) Oncoprint of MRPL13 alterations in METABRIC cohort. The different types of genetic alterations are marked with different colors. (B) Comparison of MRPL13 expression in different CNV groups. Distribution of MRPL13 CNV frequency in different grade (C), stage (D) and cell proliferation level (E) subgroups. The percentage number above the bar denotes the proportion of patients with MRPL13 gain and amplification in this subgroup. (F) Correlation between MRPL13 CNV and OS. ***p<0.001.

Abbreviations: METABRIC, the Molecular Taxonomy of Breast Cancer International Consortium; CNV, copy number variation.