Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 29;3(1):vdaa149. doi: 10.1093/noajnl/vdaa149

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 2. — Targeting glutamine metabolism reduces glioma cell growth. (A) Cell viability was performed in cancer cells treated with JAM326 or JHU-083 (72 h). Cell viability is visualized by a color scale. (B) Neurosphere forming assay was performed in cells cultured in serum-free media and treated with JHU-083. (C) Colony-forming assay was performed in adherent glioblastoma cells treated with JAM326 or JHU-083. Colony numbers are visualized by a color scale. (D) Cell viability was performed in IDH1R132H isogenic cells treated with JHU-083 (96 h). IDH1R132H protein expression was analyzed by Western blot. *P < .05; **P < .01; ***P < .001; ****P < .0001 versus Control. Doxy: doxycycline.