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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Alzheimers Dement. 2020 Sep 23;17(2):215–225. doi: 10.1002/alz.12181

Table 3.

Evidence rs10852375 and rs352214 are eQTLs in brain tissues.

Tissue rsID GENE SYMBOL A1 A2 B P FDR
TCX rs352214 ENSG00000259366 . C G −0.2201 1.02E-02 3.23E-01
TCX rs352214 ENSG00000279302 MIR3622A C G −0.1821 4.32E-02 5.78E-01
DLPFC rs352214 ENSG00000147419 CCDC25 C G −0.2001 6.15E-04 1.51E-02
DLPFC rs352214 ENSG00000120875 DUSP4 C G −0.1877 1.65E-03 3.44E-02
DLPFC rs352214 ENSG00000104290 FZD3 C G −0.7323 1.65E-38 2.10E-35
DLPFC rs352214 ENSG00000279302 MIR3622A C G −0.1268 3.85E-02 3.24E-01
CER rs10852375 ENSG00000261819 . A T −0.2354 6.41E-03 2.51E-01
CER rs10852375 ENSG00000091262 ABCC6 A T 0.1835 3.33E-02 5.33E-01
CER rs10852375 ENSG00000133393 FOPNL A T −0.1877 2.92E-02 5.10E-01
CER rs10852375 ENSG00000179889 PDXDC1 A T −0.1998 2.05E-02 4.44E-01
TCX rs10852375 ENSG00000085721 RRN3 A T −0.1831 3.36E-02 5.83E-01
DLPFC rs10852375 ENSG00000270580 . A T −0.1260 3.42E-02 3.61E-01
DLPFC rs10852375 ENSG00000227827 AC138969.2 A T 0.1915 1.20E-03 3.50E-02
DLPFC rs10852375 ENSG00000183426 NPIPA1 A T −0.1833 1.79E-03 4.87E-02
DLPFC rs10852375 ENSG00000183793 NPIPA5 A T 0.2798 2.54E-06 1.60E-04
DLPFC rs10852375 ENSG00000179889 PDXDC1 A T −0.1736 3.63E-03 8.42E-02

All results from the AMP-AD studies study where the evidence for an eQTL was nominally significant (P < 0.05; https://www.synapse.org/#!Synapse:syn17015233). Results with FDR < 0.05 are highlighted in bold font. A1: allele 1, A2: allele 2, β: beta coefficient from regression model, FDR: false discovery rate, CER: cerebellum from Mayo study, DLPFC: dorsolateral prefrontal cortex from ROSMAP study, TCX: temporal cortex from Mayo study.