Table 3.
Tissue | rsID | GENE | SYMBOL | A1 | A2 | B | P | FDR |
---|---|---|---|---|---|---|---|---|
TCX | rs352214 | ENSG00000259366 | . | C | G | −0.2201 | 1.02E-02 | 3.23E-01 |
TCX | rs352214 | ENSG00000279302 | MIR3622A | C | G | −0.1821 | 4.32E-02 | 5.78E-01 |
DLPFC | rs352214 | ENSG00000147419 | CCDC25 | C | G | −0.2001 | 6.15E-04 | 1.51E-02 |
DLPFC | rs352214 | ENSG00000120875 | DUSP4 | C | G | −0.1877 | 1.65E-03 | 3.44E-02 |
DLPFC | rs352214 | ENSG00000104290 | FZD3 | C | G | −0.7323 | 1.65E-38 | 2.10E-35 |
DLPFC | rs352214 | ENSG00000279302 | MIR3622A | C | G | −0.1268 | 3.85E-02 | 3.24E-01 |
CER | rs10852375 | ENSG00000261819 | . | A | T | −0.2354 | 6.41E-03 | 2.51E-01 |
CER | rs10852375 | ENSG00000091262 | ABCC6 | A | T | 0.1835 | 3.33E-02 | 5.33E-01 |
CER | rs10852375 | ENSG00000133393 | FOPNL | A | T | −0.1877 | 2.92E-02 | 5.10E-01 |
CER | rs10852375 | ENSG00000179889 | PDXDC1 | A | T | −0.1998 | 2.05E-02 | 4.44E-01 |
TCX | rs10852375 | ENSG00000085721 | RRN3 | A | T | −0.1831 | 3.36E-02 | 5.83E-01 |
DLPFC | rs10852375 | ENSG00000270580 | . | A | T | −0.1260 | 3.42E-02 | 3.61E-01 |
DLPFC | rs10852375 | ENSG00000227827 | AC138969.2 | A | T | 0.1915 | 1.20E-03 | 3.50E-02 |
DLPFC | rs10852375 | ENSG00000183426 | NPIPA1 | A | T | −0.1833 | 1.79E-03 | 4.87E-02 |
DLPFC | rs10852375 | ENSG00000183793 | NPIPA5 | A | T | 0.2798 | 2.54E-06 | 1.60E-04 |
DLPFC | rs10852375 | ENSG00000179889 | PDXDC1 | A | T | −0.1736 | 3.63E-03 | 8.42E-02 |
All results from the AMP-AD studies study where the evidence for an eQTL was nominally significant (P < 0.05; https://www.synapse.org/#!Synapse:syn17015233). Results with FDR < 0.05 are highlighted in bold font. A1: allele 1, A2: allele 2, β: beta coefficient from regression model, FDR: false discovery rate, CER: cerebellum from Mayo study, DLPFC: dorsolateral prefrontal cortex from ROSMAP study, TCX: temporal cortex from Mayo study.