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. 2021 Feb 25;14:1275–1289. doi: 10.2147/OTT.S293148

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© 2021 Huang et al.

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CTSG inhibits OSCC cells proliferation, migration, and invasion. (A, B) CCK8 assay indicated that high CTSG expression inhibits OSCC cells proliferation (SCC9; 3-day, P=0.0018, 4 days, P=0.0045; SCC25; 3-day, P=0.0235, 4 days, P=0.0067). (C) CTSG overexpression inhibited the clonogenicity in vitro. (D, E) CTSG overexpression reduced the migration and invasion ability of OSCC cell lines. NC stands for negative control, while CTSG-OE represents CTSG overexpression. Significant differences were supposed at *P<0.05; **P<0.01.