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. 2021 Feb 22;2021:6674283. doi: 10.1155/2021/6674283

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Copyright © 2021 Juan Luo et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Induction of Yap1 by Lin28a/b in mouse ESCs was independent of Let7 pathway. (a) Western blot analyses of total proteins from Lin28a OE mouse ESCs treated with different concentrations of Lin28-let7 inhibitor (LI71) using the indicated antibodies. (b) Western blot analyses of total proteins from Lin28a OE mouse ESCs treated with different concentrations of Lin28-let7a antagonist using the indicated antibodies. (c) Schematic of the Lin28a/b-Yap1 pathway activity regulating mouse ESC differentiation to glial lineage cells.