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. 2021 Jan 25;7(1):veab002. doi: 10.1093/ve/veab002

Figure 9.

Figure 9.

Combinations of parameters that result in pathogen prophylaxis. Vaccine effectiveness can be achieved in multiple ways. Three different paths are indicated by the different colored triangles. Each triangle represents a combination of parameters that, combined with a continual 5 per cent introduction rate or greater, result in prophylaxis. The R0P of the pathogen and the R00 of the dysfunctional vaccine was 2, while the R0V of the functional vaccine ranged from 0 to 2 depending on the cost, or reduction in transmission rate, imposed by carrying the antigen. The center circle represents a mutation rate of zero, a cost of zero, and an efficacy of 85 per cent. The outer ring represents a mutation rate of 0.001, a cost of 10 per cent and an efficacy of 1.