Table 1.

Study variables.

Variables	Type	Descriptive	Statistical model	Definition
ID	Nominal	N/Aa	No	N/A
Age	Ordinal	N/A	No	N/A
Sex	Binomial	1: Yes, 0: No	No	N/A
Study drug (exposure)	Binomial	1: Yes, 0: No	Yes	Independent
Cancer (outcome)	Binomial	1: Yes, 0: No	Yes	Dependent
Myocardial infarction	Binomial	1: Yes, 0: No	Yes	Confounding
Congestive heart failure	Binomial	1: Yes, 0: No	Yes	Confounding
Peripheral vascular disease	Binomial	1: Yes, 0: No	Yes	Confounding
Cerebrovascular disease	Binomial	1: Yes, 0: No	Yes	Confounding
Dementia	Binomial	1: Yes, 0: No	Yes	Confounding
Chronic pulmonary disease	Binomial	1: Yes, 0: No	Yes	Confounding
Rheumatic disease	Binomial	1: Yes, 0: No	Yes	Confounding
Peptic ulcer disease	Binomial	1: Yes, 0: No	Yes	Confounding
Liver disease (mild, moderate, and severe)	Binomial	1: Yes, 0: No	Yes	Confounding
Diabetes (with or without chronic complication)	Binomial	1: Yes, 0: No	Yes	Confounding
Hemiplegia or paraplegia	Binomial	1: Yes, 0: No	Yes	Confounding
Renal disease	Binomial	1: Yes, 0: No	Yes	Confounding
CCIb scores	Ordinal	N/A	Yes	Confounding
Metformin	Binomial	1: Yes, 0: No	Yes	Confounding
Aspirin	Binomial	1: Yes, 0: No	Yes	Confounding
Statin	Binomial	1: Yes, 0: No	Yes	Confounding
Matching number (case match control)	Nominal	N/A	Yes	Stratified

^aN/A: not applicable.

^bCharlson Comorbidity Index.