Table 2. Case reports detailing HER2-positive breast cancer PNDs.
Reference | HR/HER2 status | Histology | Stage | Antineuronal antibody present | PND syndrome |
---|---|---|---|---|---|
Olmez et al. [6] | HR+/HER2+ | IDC | IIA | Anti-Ri | Opsoclonus |
Myoclonus | |||||
Le May et al. [7] | HR−/HER2+ | IDC | IIB | Anti-Yo | PCD |
Dalmau et al. [8] | HR−/HER2+ | IDC | IIA | Anti-Yo | PCD |
Diamanti et al. [9] | HR+/HER2+ | IDC | IIIC | None | LMND |
Ogita et al. [10] | HR−/HER2+ | IDC | IIIC | Anti-Yo | PCD |
Dorn et al. [11] | HR−/HER2+ | IDC | IIIA | Anti-Yo | PCD |
Rupasinghe and Butler [12] | Unknown HR/HER2+ | Poorly differentiated adenocarcinoma | IIA | Anti-Yo | PCD |
Frings et al. [13] | HR−/HER2+ | ILC | IIIB | Anti-Yo | PCD |
Sancho et al. [14] | HR+/HER2+ | IDC | IIB | Anti-Yo | PCD |
HER2 = human epidermal growth factor receptor 2; PND = paraneoplastic neurologic disorder; HR = hormone receptor; IDC = invasive ductal carcinoma; ILC = invasive lobular carcinoma; PCD = paraneoplastic cerebellar degeneration; LMND = lower motor neuron disease.