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. 2020 Nov 11;24(1):106–116. doi: 10.4048/jbc.2021.24.e2

Table 2. Case reports detailing HER2-positive breast cancer PNDs.

Reference HR/HER2 status Histology Stage Antineuronal antibody present PND syndrome
Olmez et al. [6] HR+/HER2+ IDC IIA Anti-Ri Opsoclonus
Myoclonus
Le May et al. [7] HR−/HER2+ IDC IIB Anti-Yo PCD
Dalmau et al. [8] HR−/HER2+ IDC IIA Anti-Yo PCD
Diamanti et al. [9] HR+/HER2+ IDC IIIC None LMND
Ogita et al. [10] HR−/HER2+ IDC IIIC Anti-Yo PCD
Dorn et al. [11] HR−/HER2+ IDC IIIA Anti-Yo PCD
Rupasinghe and Butler [12] Unknown HR/HER2+ Poorly differentiated adenocarcinoma IIA Anti-Yo PCD
Frings et al. [13] HR−/HER2+ ILC IIIB Anti-Yo PCD
Sancho et al. [14] HR+/HER2+ IDC IIB Anti-Yo PCD

HER2 = human epidermal growth factor receptor 2; PND = paraneoplastic neurologic disorder; HR = hormone receptor; IDC = invasive ductal carcinoma; ILC = invasive lobular carcinoma; PCD = paraneoplastic cerebellar degeneration; LMND = lower motor neuron disease.